A New Amino Acid Distance

  title={A New Amino Acid Distance},
  author={Hua Tang},
For 20 amino acids, we reduced the 190 possible pairwise amino acid changes to an elementary set of 75 changes that differ by only one base pair. Based on a Markov Chain Model for substitutions, we developed an Evolutionary Index (EI) which can be computed for each of the 75 elementary changes as the likelihood of substitutions, relative to that of… CONTINUE READING