A New Agglutinable Factor Differentiating Individual Human Bloods.

  title={A New Agglutinable Factor Differentiating Individual Human Bloods.},
  author={Karl Landsteiner and Philip Levine},
  journal={Proceedings of the Society for Experimental Biology and Medicine},
  pages={600 - 602}
  • K. Landsteiner, P. Levine
  • Published 1 March 1927
  • Medicine
  • Proceedings of the Society for Experimental Biology and Medicine
By absorbing a number of anti-human blood immune sera from rabbits with the blood corpuscles of certain individuals regardless of the group, fluids were obtained from a few sera which give a sharp differentiation of individual human bloods within the common blood groups. Among 116 individuals selected from the four blood groups the distribution of the agglutinable factor (which may be designated as M) was as shown in Table II. This reaction is distinguished by its intensity from some others… 
Human Blood Groups
The blood group of a person is dependent upon the presence in his erythrocytes of specific antigens, most easily demonstrated by agglutination methods, which may or may not be found naturally in human sera.
Blood Groups of Apes and Monkeys
The study of red cell antigens of primate animals was initiated by Landsteiner and Miller in 1925. It was intensified in 1940 when it was recognized that not only apes’ and monkeys’ red cells
A Brief History of Human Blood Groups
Several investigations of blood groups from Iran, including the main blood groups ABO and Rh, as well as minor blood groups such as Duffy, Lutheran, Kell, KP, Kidd, and Xg, have been reviewed.
The Individuality of Blood and Bloodstains
The historical review reveals that it was not until the 1840's that scientists could reliably identify blood as blood, and that the ABO system, the oldest anb best known, was discovered in 1927.
Dissociation of MNSs Antigens Using Sodium Deoxycholate Fraction of Erythrocyte Membranes 1, 2
A dissociation of the MNSs blood group system has been demonstrated by sodium deoxycholate fractionation of erythrocyte membrane preparations by demonstrating that MN and Ss antigens remained soluble after 100,000 g centrifugation for donors who were heterozygous at the MN locus.
Two Blood Group M Epitopes Disclosed by Monoclonal Antibodies 1
Results indicate the existence of at least two M antigen epitopes, and G8 and E3 exhibited different specificities when used to test the red cells of nonhuman primates and erythrocytes of the rare MgMg human blood type.
A new method to prepare rabbit immune anti-M and -N sera using blood group substance trapped in autologous red cell ghost as an immunogen.
To prepare anti-M and -N of a sufficient potency, M or N substance trapped in autologous ghost was intravenously administered to rabbits and it was considered that intravenous injection of the antigen trapped in ghost is useful for preparing hemagglutinin of sufficient titers.
A New Method to Prepare AntiM and-N Sera Using Trapped in Autologous Red as an Immunogen Rabbit Immune Blood Group Substance Cell Ghost
YoKOI, T., IWASA, M. and SAGISAKA, K. A New Method to Prepare Rabbit Immune Anti-M and -N Sera Using Blood Group Substance Trapped in Autologous Red Cell Ghost as an Immunogen. Tohoku J. exp. Med.,
Blood group serology--the first four decades (1900--1939).
The mystique which then surrounded blood group serology is explained in terms of the confusion aroused by the existence of different nomenclatures for the ABO groups, and the lack of techniques for demonstration of (what are now known as) IgG antibodies.
MN determination in bloodstains--selective destruction of cross-reacting activity.
Forensic serology is an expansion of this study and encompasses not only serology but the essentials of biochemistry, immunohematology, immunology, and immunochemistry.