A Neuroblastoma X Glioma Hybrid Cell Line with Morphine Receptors

@inproceedings{KleeANX,
  title={A Neuroblastoma X Glioma Hybrid Cell Line with Morphine Receptors},
  author={W A Klee and Marshall W. Nirenberg}
}
A neuroblastoma X glioma hybrid cell line with well-developed neural properties was found that has high-affinity morphine receptors. The average cell contains approximately 3 X 105 receptors. In contrast, parent cells and other neuroblastoma or hybrid cell lines tested had few or no morphine receptors. Membrane preparations that bind narcotic analgesics such as morphine and its congeners have been described by a number of laboratories (1-9). Such binding satisfies the criteria first enunciated… CONTINUE READING
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