A Neural Marker of Obsessive-Compulsive Disorder from Whole-Brain Functional Connectivity

  title={A Neural Marker of Obsessive-Compulsive Disorder from Whole-Brain Functional Connectivity},
  author={Yu Takagi and Yuki Sakai and Giuseppe Lisi and Noriaki Yahata and Yoshinari Abe and Seiji Nishida and Takashi Nakamae and Jun Morimoto and Mitsuo Kawato and Jin Narumoto and Saori C. Tanaka},
  journal={Scientific Reports},
Obsessive-compulsive disorder (OCD) is a common psychiatric disorder with a lifetime prevalence of 2–3%. Recently, brain activity in the resting state is gathering attention for exploring altered functional connectivity in psychiatric disorders. Although previous resting-state functional magnetic resonance imaging studies investigated the neurobiological abnormalities of patients with OCD, there are concerns that should be addressed. One concern is the validity of the hypothesis employed. Most… 
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