A Natural Bacterium-Produced Membrane-Bound Nanocarrier for Drug Combination Therapy

Abstract

To minimize the non-specific toxicity of drug combination during cancer therapy, we prepared a new system synthesized from bacteria to deliver the anticancer drugs cytosine arabinoside (Ara-C) and daunorubicin (DNR). In this study, we selected genipin (GP) and poly-l-glutamic acid (PLGA) as dual crosslinkers. Herewith, we demonstrated the preparation… (More)
DOI: 10.3390/ma9110889

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