A Narrative Review of Aspirin Resistance in VTE Prophylaxis for Orthopaedic Surgery

  title={A Narrative Review of Aspirin Resistance in VTE Prophylaxis for Orthopaedic Surgery},
  author={Nameer van Oosterom and Michael A. Barras and Robert J Bird and Iulian Nusem and Neil Cottrell},
  pages={1889 - 1899}
Total hip arthroplasties (THA) and total knee arthroplasties (TKA) confer one of the highest risks for developing venous thromboembolism (VTE) and pharmacological prophylaxis is imperative to help mitigate the risks. Aspirin is the most cost-effective medication for VTE prophylaxis, and its use post-THA/TKA has grown in popularity. Aspirin resistance is categorised as clinical or laboratory resistance with obesity, advancing age, diabetes mellitus, dyslipidaemia and inflammatory diseases… 

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