A Narrative Review of Aspirin Resistance in VTE Prophylaxis for Orthopaedic Surgery

@article{vanOosterom2020ANR,
  title={A Narrative Review of Aspirin Resistance in VTE Prophylaxis for Orthopaedic Surgery},
  author={Nameer van Oosterom and Michael A. Barras and Robert J Bird and Iulian Nusem and Neil Cottrell},
  journal={Drugs},
  year={2020},
  volume={80},
  pages={1889 - 1899}
}
Total hip arthroplasties (THA) and total knee arthroplasties (TKA) confer one of the highest risks for developing venous thromboembolism (VTE) and pharmacological prophylaxis is imperative to help mitigate the risks. Aspirin is the most cost-effective medication for VTE prophylaxis, and its use post-THA/TKA has grown in popularity. Aspirin resistance is categorised as clinical or laboratory resistance with obesity, advancing age, diabetes mellitus, dyslipidaemia and inflammatory diseases… 
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Asia-Pacific venous thromboembolism consensus in knee and hip arthroplasty and hip fracture surgery: Part 1. Diagnosis and risk factors
TLDR
An AP consensus agreement on VTE prophylaxis in knee and hip arthroplasty and hip fracture surgery in Asian patients among AP orthopedic experts is obtained in a one-year period to provide Orthopedic surgeons who practice in the AP Region appropriate options for VTE diagnosis and prevention methods that benefit their patients with fewer complications.
Performance comparison of aspirin assay between Anysis and VerifyNow: Assessment of therapeutic platelet inhibition in patients with cardiac diseases
TLDR
Anysis-aspirin, a novel aspirin assay for assessing platelet inhibition, showed excellent agreement with VerifyNow- aspirin with high accuracy and precision and would be used as a point-of-care test to assess aspirin non-responsiveness and abnormal platelet reactivity.

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