A NOTE ON THE PRODUCTION OF ANTIPNEUMOCOCCUS SERA

@article{Wadsworth2003ANO,
  title={A NOTE ON THE PRODUCTION OF ANTIPNEUMOCOCCUS SERA},
  author={Augustus B. Wadsworth and Mary Butler Kirkbride},
  journal={The Journal of Experimental Medicine},
  year={2003},
  volume={25},
  pages={629 - 632}
}
Horses immunized to Type I pneumococci developed serum, 0.1 cc. of which protected against 0.5 cc. of a virulent culture, 0.000001 cc. of which killed mice in less than 40 hours. Protective tests of serum from horses immunized to Type II organisms varied, 0.1 cc. protecting, however, in certain instances against 0.1 and 0.01 cc. of virulent homologous culture. Types I and II sera obtained in our experiments with culture sediment and whole culture did not vary markedly for a given type and… CONTINUE READING

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