A NEW CATIONIC ANTIMICROBIAL AGENT, N‐DODECYL‐4‐AMINOQUINALDINIUM ACETATE (LAUROLINIUM ACETATE)

@article{Cox1963ANC,
  title={A NEW CATIONIC ANTIMICROBIAL AGENT, N‐DODECYL‐4‐AMINOQUINALDINIUM ACETATE (LAUROLINIUM ACETATE)},
  author={W. A. Cox and P. D'arcy},
  journal={Journal of Pharmacy and Pharmacology},
  year={1963},
  volume={15}
}
  • W. A. Cox, P. D'arcy
  • Published 1963
  • Medicine, Chemistry
  • Journal of Pharmacy and Pharmacology
  • The properties of a new cationic antimicrobial agent, N‐dodecyl‐4‐aminoquinaldinium acetate (laurolinium acetate, Laurodin) are described. It has bacteriostatic and bactericidal activity against Gram‐positive and Gram‐negative bacteria, fungi and some protozoa. Its activity is antagonised by anionic substances but some is retained in the presence of organic matter. The compound is well suited for topical use but is too toxic for parenteral use. 
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