A NEIL1 single nucleotide polymorphism (rs4462560) predicts the risk of radiation‐induced toxicities in esophageal cancer patients treated with definitive radiotherapy

@article{Chen2013ANS,
  title={A NEIL1 single nucleotide polymorphism (rs4462560) predicts the risk of radiation‐induced toxicities in esophageal cancer patients treated with definitive radiotherapy},
  author={Y. Chen and Meiling Zhu and Z. Zhang and G. Jiang and X. Fu and M. Fan and M. Sun and Q. Wei and K. Zhao},
  journal={Cancer},
  year={2013},
  volume={119}
}
To assess the association between single nucleotide polymorphisms (SNPs) of base‐excision repair genes and clinical outcomes, the roles of genetic variants of 3 selected genes—flap structure‐specific endonuclease 1 (FEN1), 8‐hydroxyguanine DNA glycosylase (hOGG1), and nei endonuclease VIII‐like 1 (NEIL1)—were investigated in radiation‐induced esophageal toxicity (RIET), radiation pneumonitis (RP), and overall survival (OS) after radio(chemo)therapy in patients with esophageal squamous cell… Expand
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