A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases

@inproceedings{Berenstein2016AMN,
  title={A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases},
  author={Ariel J. Berenstein and Mar{\'i}a P. Magari{\~n}os and Ariel Chernomoretz and Fern{\'a}n Ag{\"u}ero and Timothy G Geary},
  booktitle={PLoS neglected tropical diseases},
  year={2016}
}
  • Ariel J. Berenstein, María P. Magariños, +2 authors Timothy G Geary
  • Published in
    PLoS neglected tropical…
    2016
  • Biology, Medicine
  • Drug development for neglected diseases has been historically hampered due to lack of market incentives. The advent of public domain resources containing chemical information from high throughput screenings is changing the landscape of drug discovery for these diseases. In this work we took advantage of data from extensively studied organisms like human, mouse, E. coli and yeast, among others, to develop a novel integrative network model to prioritize and identify candidate drug targets in… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    8
    Twitter Mentions

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 15 CITATIONS

    Computational Methods for Drug Repurposing

    VIEW 15 EXCERPTS
    CITES METHODS & BACKGROUND
    HIGHLY INFLUENCED

    Nine quick tips for analyzing network data

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 122 REFERENCES