A Multicentre Trial to Evaluate the Efficacy and Tolerability of α-Glycerylphosphorylcholine versus Cytosine Diphosphocholine in Patients with Vascular Dementia

@article{Perri1991AMT,
  title={A Multicentre Trial to Evaluate the Efficacy and Tolerability of $\alpha$-Glycerylphosphorylcholine versus Cytosine Diphosphocholine in Patients with Vascular Dementia},
  author={Raoul Di Perri and Giovanni Coppola and L A Ambrosio and Antonino Grasso and F. M. Puca and Mimma Rizzo},
  journal={Journal of International Medical Research},
  year={1991},
  volume={19},
  pages={330 - 341}
}
An open clinical trial was carried out to compare the efficacy and the tolerability of 1 g/day α-glycerylphosphorylcholine (α-GPC) with 1 g/day cytosine diphosphocholine (CDP) both given intramuscularly for 90 days in 120 patients with mild to moderate vascular dementia. The clinical evaluation, carried out at the start as well as halfway through (45 days) and at the end of treatment (90 days), was expressed by psychometric tests (modified Parkside behaviour rating scale, Sandoz clinical… 

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