A Multicenter Evaluation of a Closed-Loop Anesthesia Delivery System: A Randomized Controlled Trial.

@article{Puri2016AME,
  title={A Multicenter Evaluation of a Closed-Loop Anesthesia Delivery System: A Randomized Controlled Trial.},
  author={Goverdhan Dutt Puri and Preethy Joseph Mathew and Indranil Biswas and Amitabh Dutta and Jayashree Sood and Satinder Gombar and Sanjeev Palta and Morup Tsering and Parshotam lal Gautam and Aveek Jayant and Inderjeet Arora and Vishal Bajaj and Tamanna Punia and Gurjit Singh},
  journal={Anesthesia and analgesia},
  year={2016},
  volume={122 1},
  pages={
          106-14
        }
}
BACKGROUND Closed-loop systems for anesthesia delivery have been shown to outperform traditional manual control in different clinical settings. The present trial was aimed at evaluating the feasibility and efficacy of Bispectral Index (BIS)-guided closed-loop anesthesia delivery system (CLADS) in comparison with manual control across multiple centers in India. METHODS Adult patients scheduled for major surgical procedures of an expected duration of 1 to 3 hours were randomized across 6 sites… CONTINUE READING

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