A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT.

@article{He2005AMC,
  title={A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT.},
  author={Bin He and Yong Du and Xiyun Song and William Paul Segars and Eric C. Frey},
  journal={Physics in medicine and biology},
  year={2005},
  volume={50 17},
  pages={4169-85}
}
Accurate estimation of the 3D in vivo activity distribution is important for dose estimation in targeted radionuclide therapy (TRT). Although SPECT can potentially provide such estimates, SPECT without compensation for image degrading factors is not quantitatively accurate. In this work, we evaluated quantitative SPECT (QSPECT) reconstruction methods that include compensation for various physical effects. Experimental projection data were obtained using a GE VH/Hawkeye system and an RSD torso… CONTINUE READING

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