A Monocyte chemoattractant protein-1 (MCP-1) polymorphism and outcome after renal transplantation.

@article{Krger2002AMC,
  title={A Monocyte chemoattractant protein-1 (MCP-1) polymorphism and outcome after renal transplantation.},
  author={Bernd Kr{\"u}ger and Bernd Schr{\"o}ppel and Rami Ashkan and Brad A. Marder and Carl Zuelke and Barbara Murphy and Bernhard Kraemer and Michael Fischereder},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2002},
  volume={13 10},
  pages={2585-9}
}
Among the factors modulating transplant rejection and cardiovascular disease, chemokines and their respective receptors deserve special attention. In this respect, increased expression of MCP-1 and the corresponding receptor CCR2 have been demonstrated in renal transplant rejection and coronary artery disease. The impact of the MCP-1-2518G and CCR2-64I genotypes on renal allograft function was investigated in 232 patients who underwent transplantation over an 11-yr period. Genomic DNA was… CONTINUE READING
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