A Molecularly Complete Planar Bacterial Outer Membrane Platform

  title={A Molecularly Complete Planar Bacterial Outer Membrane Platform},
  author={Chih-Yun Hsia and Linxiao Chen and Rohit R. Singh and Matthew P DeLisa and Susan Daniel},
  booktitle={Scientific reports},
The bacterial outer membrane (OM) is a barrier containing membrane proteins and liposaccharides that fulfill crucial functions for Gram-negative bacteria. With the advent of drug-resistant bacteria, it is necessary to understand the functional role of this membrane and its constituents to enable novel drug designs. Here we report a simple method to form an OM-like supported bilayer (OM-SB), which incorporates native lipids and membrane proteins of gram-negative bacteria from outer membrane… CONTINUE READING
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