A Molecular Rhythm Mediating Circadian Clock Output in Drosophila

@article{McNeil1998AMR,
  title={A Molecular Rhythm Mediating Circadian Clock Output in Drosophila},
  author={Gerard P. McNeil and Xiaolan Zhang and Ginka Genova and F A Jackson},
  journal={Neuron},
  year={1998},
  volume={20},
  pages={297-303}
}
Analysis of the Drosophila lark gene indicates that it encodes an RNA-binding protein that functions as a regulatory element of the circadian clock output pathway controlling adult eclosion. We now demonstrate that the lark RNA-binding protein oscillates in abundance during the circadian cycle; importantly, the phasing of the lark rhythm is consistent with gene-dosage studies, which indicate that the protein behaves as a repressor molecule. The lark protein rhythm persists in constant… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 45 references

A novel circadianly

  • R. N. Van Gelder, M. A. Krasnow
  • 1996
Highly Influential
4 Excerpts

ELAV, a Drosophila

  • S. P. Koushika, M. J. Lisbin, K. White
  • 1996
Highly Influential
8 Excerpts

A lightentrainment mechanism for the Drosophila circadian clock

  • J. Majercak, D. Kalderon, I. Edery
  • Nature
  • 1997
1 Excerpt

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