A Molecular “Zipper” for Microtubules

@article{Kikkawa2006AM,
  title={A Molecular “Zipper” for Microtubules},
  author={Masahide Kikkawa and Zoltan Metlagel},
  journal={Cell},
  year={2006},
  volume={127},
  pages={1302-1304}
}
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10 Citations
Background Citations
2

10 Citations

Cytoskeleton: Tracking the weakest link
  • E. Kritikou
  • Biology
    Nature Reviews Molecular Cell Biology
  • 2007
TLDR
It is reported that the fission yeast +TIP, Mal3, interacts with microtubules in a very different way from other MAPs — Mal3 binds to and stabilizesmicrotubules through a specific interaction with the microtubule-lattice seam, which is potentially the weakest part of the micro Tubule.
Mechanochemical Modeling of Dynamic Microtubule Growth Involving Sheet-to-Tube Transition
TLDR
A Tetris-like growth style of microtubules is described: the stochastic tubulin assembly is regulated by energy and harmonized with the seam zipping such that the sheet keeps a practically constant length during growth.
Funktionelle Charakterisierung der Interaktion des COP9-Signalosoms mit dem Mikrotubuli-bindenden Protein EB1
6
Environmentally responsive histidine-carboxylate zipper formation between proteins and nanoparticles.
TLDR
The creation of a reversible multivalent supramolecular "zipper" recognition motif between gold nanoparticles and proteins is reported, which can be tuned through His-tag length, and offers unique binding profiles based on the pH and electrolyte concentration of the medium.
Superior cervical ganglion-10 protein as a molecular effector of c-Jun N-terminal kinase 1: implications for the therapeutic targeting of Jun N-terminal kinase in nerve regeneration
TLDR
A model reconciling the microtubule regulatory properties of superior cervical ganglion protein 10 with its role as a JNK effector of regeneration is proposed and remaining issues to be resolved are highlighted.
Etude fonctionnelle de la protéine associée aux microtubules XMAP215/ch-TOG
Resume Les proteines XMAP215/ch-TOG appartiennent a une famille de proteines associees aux microtubules (MAPs), bien conservee tout au long de l'evolution, la famille XMAP215/Dis1. Cette famille joue…
Powerful Scientific Projective Technique KANEHA-TIR-Ψ uses an “Integrated and Intensified-Ψ Entangled Quantum Computing”
We present scientific basis of Kapil-Neha Total Internal Reflection Quantum Mechanical Projection Wave function Ψ Technique (KANEHA-TIR-Ψ Projective Technique). KANEHATIR-Ψ projective technique uses…
Quantum brain-time matrix — The correlation between brain-mind-time with quantum spin and quantum entanglement: Quantum computation of the brain and representation as a matrix
The relation between Brain or Mind and Consciousness is unknown for quite a while. Several Theories and Compositions have been made by Neurologists all over the Globe; still, the relation is still…
Microtubule Dynamics in S.cerevisiae
Controlled fabrication of organic nanotubes via self-assembly of non-symmetric bis-acylurea
We present novel non-symmetric bis-acylurea organogelators that self-assemble into hollow tubular nanostructures upon cooling in solutions. The bis-acylureas have aliphatic end groups of different…

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