A Model of Lipid-Free Apolipoprotein A-I Revealed by Iterative Molecular Dynamics Simulation

Abstract

Apolipoprotein A-I (apo A-I), the major protein component of high-density lipoprotein, has been proven inversely correlated to cardiovascular risk in past decades. The lipid-free state of apo A-I is the initial stage which binds to lipids forming high-density lipoprotein. Molecular models of lipid-free apo A-I have been reported by methods like X-ray… (More)
DOI: 10.1371/journal.pone.0120233

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@inproceedings{Zhang2015AMO, title={A Model of Lipid-Free Apolipoprotein A-I Revealed by Iterative Molecular Dynamics Simulation}, author={Xing Zhang and Dongsheng Lei and Lei Zhang and Matthew J. Rames and Shengli Zhang}, booktitle={PloS one}, year={2015} }