A Model for Fatty Acid Transport into the Brain

  title={A Model for Fatty Acid Transport into the Brain},
  author={James Alexander George Hamilton and Kellen Brunaldi},
  journal={Journal of Molecular Neuroscience},
A key function of fatty acid (FA) transport into the brain is to supply polyunsaturated fatty acids (PUFA) that are not synthesized in brain cells but are essential signaling molecules and components of the phospholipid membrane. In addition, common dietary FAs such as palmitic acid are also rapidly taken up by the brain and esterified to phospholipids or oxidized to provide cellular energy. Most evidence shows that FA crossing the blood brain barrier (BBB) is derived mainly from FA/albumin… CONTINUE READING
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