A Mitochondrial Perspective of Chronic Obstructive Pulmonary Disease Pathogenesis

@inproceedings{Kang2016AMP,
  title={A Mitochondrial Perspective of Chronic Obstructive Pulmonary Disease Pathogenesis},
  author={Min-Jong Kang and Gerald S Shadel},
  booktitle={Tuberculosis and respiratory diseases},
  year={2016}
}
  • Min-Jong Kang, Gerald S Shadel
  • Published in
    Tuberculosis and respiratory…
    2016
  • Medicine
  • Chronic obstructive pulmonary disease (COPD) encompasses several clinical syndromes, most notably emphysema and chronic bronchitis. Most of the current treatments fail to attenuate severity and progression of the disease, thereby requiring better mechanistic understandings of pathogenesis to develop disease-modifying therapeutics. A number of theories on COPD pathogenesis have been promulgated wherein an increase in protease burden from chronic inflammation, exaggerated production of reactive… CONTINUE READING

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