A Miniature Low-Power Multi-Biomarker-Based Brain Sensor for Closed-Loop DBS

  title={A Miniature Low-Power Multi-Biomarker-Based Brain Sensor for Closed-Loop DBS},
  author={Mahboubeh Parastarfeizabadi and Abbas Z. Kouzani},
  journal={IEEE Sensors Journal},
Thus far only a few closed-loop deep brain stimulation (DBS) devices have been developed. These devices measure one biomarker for closing the stimulation loop. However, there are many types of neurological disorders requiring different biomarkers to be monitored. Therefore, a multiple-biomarker-based neural sensing device is needed to achieve closed-loop DBS for multiple disorders. This paper presents the design, fabrication, and in vitro evaluation of a miniature multi-biomarker-based neural… 

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