A Microstructurally Motivated Model of Arterial Wall Mechanics with Mechanobiological Implications

@article{Bellini2013AMM,
  title={A Microstructurally Motivated Model of Arterial Wall Mechanics with Mechanobiological Implications},
  author={C Bellini and Jacopo Ferruzzi and Sara Roccabianca and Elena S. Di Martino and Jay D. Humphrey},
  journal={Annals of Biomedical Engineering},
  year={2013},
  volume={42},
  pages={488-502}
}
Through mechanobiological control of the extracellular matrix, and hence local stiffness, smooth muscle cells of the media and fibroblasts of the adventitia play important roles in arterial homeostasis, including adaptations to altered hemodynamics, injury, and disease. We present a new approach to model arterial wall mechanics that seeks to define better the mechanical environments of the media and adventitia while avoiding the common prescription of a traction-free reference configuration… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Biome - chanical phenotyping of central arteries in health and disease : advantages of and methods for murine models

  • J. Ferruzzi, J. D. Humphrey
  • Ann . Biomed . Eng .
  • 2013

A constitutive model for vascular tissue that integrates fibril , fiber and continuum levels with application to the isotropic and passive properties of the infrarenal aorta

  • J. C. McGrath, C. Deighan, +6 authors C. J. Daly
  • J . Biomech .
  • 2011

Similar Papers

Loading similar papers…