A Microfluidic Study of Megakaryocytes Membrane Transport Properties to Water and Dimethyl Sulfoxide at Suprazero and Subzero Temperatures.

@article{Tseng2011AMS,
  title={A Microfluidic Study of Megakaryocytes Membrane Transport Properties to Water and Dimethyl Sulfoxide at Suprazero and Subzero Temperatures.},
  author={Hsiu-Yang Tseng and Sijie Sun and Zhiquan Shu and Weiping Ding and J Reems and Dayong Gao},
  journal={Biopreservation and biobanking},
  year={2011},
  volume={9 4},
  pages={355-362}
}
Megakaryocytes (MKs) are the precursor cells of platelets. Cryopreservation of MKs is critical for facilitating research investigations about the biology of this important cell and may help for scaling-up ex-vivo production of platelets from MKs for clinical transfusion. Determining membrane transport properties of MKs to water and cryoprotectant agents (CPAs) is essential for developing optimal conditions for cryopreserving MKs. To obtain these unknown parameters, membrane transport properties… CONTINUE READING