A Metabolomics Approach Reveals Immunomodulatory Effects of Proteinaceous Molecules Derived From Gut Bacteria Over Human Peripheral Blood Mononuclear Cells

@inproceedings{CambeiroPrez2018AMA,
  title={A Metabolomics Approach Reveals Immunomodulatory Effects of Proteinaceous Molecules Derived From Gut Bacteria Over Human Peripheral Blood Mononuclear Cells},
  author={Noelia Cambeiro-P{\'e}rez and Claudio Hidalgo-Cantabrana and Marco Antonio Moro-Garc{\'i}a and Rebeca Alonso-Arias and Jesus Simal-Gandara and Borja S{\'a}nchez and Elena Mart{\'i}nez-Carballo},
  booktitle={Front. Microbiol.},
  year={2018}
}
There are strong evidences that probiotics influence the immune status of the host, in a strain-specific manner, acting in the gastrointestinal tract. On the hypothesis that certain extracellular proteins and peptides from gut bacteria may mediate part of this immunomodulation and assuming they are able to diffuse through the mucus layer and interact with immune cells we have developed this work. Our study attempts to understand the immunomodulatory mechanisms of (i) Pext, the extracellular… CONTINUE READING
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