A Mechanosensory Pathway to the Drosophila Circadian Clock

@article{Simoni2014AMP,
  title={A Mechanosensory Pathway to the Drosophila Circadian Clock},
  author={Alekos Simoni and Winterberg Wolfgang and Matthew P. Topping and Ryan G. Kavlie and Ralf Stanewsky and Joerg T Albert},
  journal={Science},
  year={2014},
  volume={343},
  pages={525-528}
}
Circadian clocks attune the physiology of virtually all living organisms to the diurnal cycles of their environments. In metazoan animals, multiple sensory input pathways have been linked to clock synchronization with the environmental cycle (entrainment). Extrinsic entrainment cues include light and temperature. We show that (12-hour:12-hour) cycles of vibration and silence (VS) are sufficient to synchronize the daily locomotor activity of wild-type Drosophila melanogaster. Behavioral… CONTINUE READING
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Acknowledgments This work was supported by grants from the BBSRC (BB/H001204/1 to R.S. and BB/G004455/1 to J.T.A.), the HFSP (to J.T.A) and the EU FP6 Integrated Project ‘EUCLOCK

  • Y. Citri
  • Nature 326,
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