A Mechanism for Nuclear Positioning in Fission Yeast Based on Microtubule Pushing

@article{Tran2001AMF,
  title={A Mechanism for Nuclear Positioning in Fission Yeast Based on Microtubule Pushing},
  author={P T Tran and Lorraine Marsh and Val{\'e}rie Doye and Shinya Inou{\'e} and Fred Chang},
  journal={The Journal of Cell Biology},
  year={2001},
  volume={153},
  pages={397 - 412}
}
The correct positioning of the nucleus is often important in defining the spatial organization of the cell, for example, in determining the cell division plane. In interphase Schizosaccharomyces pombe cells, the nucleus is positioned in the middle of the cylindrical cell in an active microtubule (MT)-dependent process. Here, we used green fluorescent protein markers to examine the dynamics of MTs, spindle pole body, and the nuclear envelope in living cells. We find that interphase MTs are… CONTINUE READING
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