A Mathematical Model of Thyroid Disease Response to Radiotherapy

@article{GagoArias2021AMM,
  title={A Mathematical Model of Thyroid Disease Response to Radiotherapy},
  author={Araceli Gago-Arias and Sara Neira and Filippo Terragni and Juan Pardo-Montero},
  journal={Mathematics},
  year={2021}
}
We present a mechanistic biomathematical model of molecular radiotherapy of thyroid disease. The general model consists of a set of differential equations describing the dynamics of different populations of thyroid cells with varying degrees of damage caused by radiotherapy (undamaged cells, sub-lethally damaged cells, doomed cells, and dead cells), as well as the dynamics of thyroglobulin and antithyroglobulin autoantibodies, which are important surrogates of treatment response. The model is… 

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