A MRI Prospective Survey on Heart and Liver Iron and Cardiac Function in Thalassemia Major Patients Treated with Deferasirox Versus Deferiprone and Desferrioxamine in Monotherapy

@inproceedings{Pepe2016AMP,
  title={A MRI Prospective Survey on Heart and Liver Iron and Cardiac Function in Thalassemia Major Patients Treated with Deferasirox Versus Deferiprone and Desferrioxamine in Monotherapy},
  author={Alessia Pepe and Laura Pistoia and Liana Cuccia and Monica Fortini and Vincenzo Caruso and Rosamaria Rosso and Saveria Campisi and Angelo Peluso and Francesco Sorrentino and Aurelio Maggio and Vincenzo Positano and Giuseppe Peritore and Antonella Meloni},
  year={2016}
}
Background: No prospective data are available about the efficacy of deferasirox versus deferiprone and desferrioxamine in monotherapy. Our study aimed to prospectively assess the efficacy of deferasirox versus deferiprone and desferrioxamine in monotherapy in a large cohort of thalassemia major (TM) patients by quantitative Magnetic Resonance (MR). Methods: Among the 2551 TM patients enrolled in the MIOT (Myocardial Iron Overload in Thalassemia) network we selected those with an MR follow up… CONTINUE READING