A Long Noncoding RNA ZEB1-AS1 Promotes Tumorigenesis and Predicts Poor Prognosis in Glioma

@article{Lv2016ALN,
  title={A Long Noncoding RNA ZEB1-AS1 Promotes Tumorigenesis and Predicts Poor Prognosis in Glioma},
  author={Qiao-li Lv and Lei Hu and Shu-Hui Chen and Bao Sun and Mengjin Fu and Chong-zhen Qin and Qiang Qu and Guihua Wang and Chen-Jie He and Hong-hao Zhou},
  journal={International Journal of Molecular Sciences},
  year={2016},
  volume={17}
}
  • Q. Lv, Lei Hu, +7 authors H. Zhou
  • Published 30 August 2016
  • Biology, Medicine
  • International Journal of Molecular Sciences
Emerging studies show that long noncoding RNAs (lncRNAs) have important roles in carcinogenesis. lncRNA ZEB1 antisense 1 (ZEB1-AS1) is a novel lncRNA, whose clinical significance, biological function, and underlying mechanism remains unclear in glioma. Here, we found that ZEB1-AS1 was highly expressed in glioma tissues, being closely related to clinical stage of glioma. Moreover, patients with high ZEB1-AS1 levels had poor prognoses, with the evidence provided by multivariate Cox regression… Expand
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