A Long Journey from Minimum Inhibitory Concentration Testing to Clinically Predictive Breakpoints: Deterministic and Probabilistic Approaches in Deriving Breakpoints

@article{Dalhoff2009ALJ,
  title={A Long Journey from Minimum Inhibitory Concentration Testing to Clinically Predictive Breakpoints: Deterministic and Probabilistic Approaches in Deriving Breakpoints},
  author={Axel Dalhoff and Paul G. Ambrose and Johan W. Mouton},
  journal={Infection},
  year={2009},
  volume={37},
  pages={296-305}
}
AbstractSince the origin of an "‘International Collaborative Study on Antibiotic Sensitivity Testing’" in 1971, considerable advancement has been made to standardize clinical susceptibility testing procedures of antimicrobial agents. However, a consensus on the methods to be used and interpretive criteria was not reached, so the results of susceptibility testing were discrepant. Recently, the European Committee on Antimicrobial Susceptibility Testing achieved a harmonization of existing methods… 

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