A Light-Actuated Nanovalve Derived from a Channel Protein

@article{Koer2005ALN,
  title={A Light-Actuated Nanovalve Derived from a Channel Protein},
  author={Armağan Koçer and Martin Walko and Wim Meijberg and Ben L. Feringa},
  journal={Science},
  year={2005},
  volume={309},
  pages={755 - 758}
}
Toward the realization of nanoscale device control, we report a molecular valve embedded in a membrane that can be opened by illumination with long-wavelength ultraviolet (366 nanometers) light and then resealed by visible irradiation. The valve consists of a channel protein, the mechanosensitive channel of large conductance (MscL) from Escherichia coli, modified by attachment of synthetic compounds that undergo light-induced charge separation to reversibly open and close a 3-nanometer pore… Expand

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