A Key Role of microRNA-29b for the Suppression of Colon Cancer Cell Migration by American Ginseng

@inproceedings{Poudyal2013AKR,
  title={A Key Role of microRNA-29b for the Suppression of Colon Cancer Cell Migration by American Ginseng},
  author={D. Sharma Poudyal and Xiangli Cui and Phuong Mai Le and Anne B. Hofseth and Anthony J. Windust and Mitzi Nagarkatti and Prakash Nagarkatti and Aaron J. Schetter and Curtis C. Harris and Lorne J. Hofseth},
  booktitle={PloS one},
  year={2013}
}
Metastasis of colon cancer cells increases the risk of colon cancer mortality. We have recently shown that American ginseng prevents colon cancer, and a Hexane extract of American Ginseng (HAG) has particularly potent anti-inflammatory and anti-cancer properties. Dysregulated microRNA (miR) expression has been observed in several disease conditions including colon cancer. Using global miR expression profiling, we observed increased miR-29b in colon cancer cells following exposure to HAG. Since… CONTINUE READING
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