A Key Role of microRNA-29b for the Suppression of Colon Cancer Cell Migration by American Ginseng

  title={A Key Role of microRNA-29b for the Suppression of Colon Cancer Cell Migration by American Ginseng},
  author={D. Poudyal and Xiangli Cui and Phuong M. Le and Anne B. Hofseth and A. Windust and M. Nagarkatti and P. Nagarkatti and A. Schetter and C. Harris and L. Hofseth},
  journal={PLoS ONE},
  • D. Poudyal, Xiangli Cui, +7 authors L. Hofseth
  • Published 2013
  • Medicine
  • PLoS ONE
  • Metastasis of colon cancer cells increases the risk of colon cancer mortality. We have recently shown that American ginseng prevents colon cancer, and a Hexane extract of American Ginseng (HAG) has particularly potent anti-inflammatory and anti-cancer properties. Dysregulated microRNA (miR) expression has been observed in several disease conditions including colon cancer. Using global miR expression profiling, we observed increased miR-29b in colon cancer cells following exposure to HAG. Since… CONTINUE READING
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