A Key Cytoskeletal Regulator of Ubiquitination Amplifies TGF Signaling During Mouse 1 Developmental Vascular Patterning

  • Ronak Shetty, Divyesh Joshi, +8 authors Kasturi Nagar
  • Published 2016


23 Vascular development involves de novo formation of a capillary plexus, which is then pruned and 24 remodeled by angiogenic events. Cytoskeletal remodeling and directional endothelial migration are 25 essential for developmental and pathological angiogenesis. Smad-dependent TGF signaling controls 26 vascular patterning and is negatively regulated by… (More)