A Keratinocyte’s Course of Life

@article{Houben2006AKC,
  title={A Keratinocyte’s Course of Life},
  author={Evi Houben and Kristien de Paepe and Vera Maria Rogiers},
  journal={Skin Pharmacology and Physiology},
  year={2006},
  volume={20},
  pages={122 - 132}
}
An adequate permeability barrier function of the mammalian epidermis is guaranteed by the characteristic architecture of the stratum corneum. This uppermost layer consists of a highly organized extracellular lipid compartment which is tightly joined to the corneocytes. The generation of the extracellular lipid compartment and the transformation of the keratinocytes into corneocytes are the main features of epidermal differentiation. However, equally important is the continuous renewal of the… 
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