A Humanized Mouse Model of Tuberculosis

@article{Calderon2013AHM,
  title={A Humanized Mouse Model of Tuberculosis},
  author={Veronica Elena Calderon and Gustavo A. Valbuena and Yenny G{\'o}ez and Barbara Judy and Matthew B. Huante and Putri Sutjita and R. Katie Johnston and Don Mark Estes and Robert L. Hunter and Jeffrey K. Actor and Jeffrey D. Cirillo and Janice J Endsley},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
Mycobacterium tuberculosis (M.tb) is the second leading infectious cause of death worldwide and the primary cause of death in people living with HIV/AIDS. There are several excellent animal models employed to study tuberculosis (TB), but many have limitations for reproducing human pathology and none are amenable to the direct study of HIV/M.tb co-infection. The humanized mouse has been increasingly employed to explore HIV infection and other pathogens where animal models are limiting. Our goal… 
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