• DOI:10.7326/0003-4819-159-4-201308200-00005
• Corpus ID: 14458343

A Home-Based Intervention to Reduce Depressive Symptoms and Improve Quality of Life in Older African Americans

@article{Gitlin2013AHI,
  title={A Home-Based Intervention to Reduce Depressive Symptoms and Improve Quality of Life in Older African Americans},
  author={Laura N. Gitlin and Lynn Fields Harris and Megan C. McCoy and Nancy L. Chernett and Laura T. Pizzi and Eric Jutkowitz and Ed Hess and Walter W. Hauck},
  journal={Annals of Internal Medicine},
  year={2013},
  volume={159},
  pages={243 - 252}
}

• L. Gitlin, L. Harris, +5 authors W. Hauck
• Published 20 August 2013
• Psychology, Medicine
• Annals of Internal Medicine

BACKGROUND
Effective care models for treating older African Americans with depressive symptoms are needed.

OBJECTIVE
To determine whether a home-based intervention alleviates depressive symptoms and improves quality of life in older African Americans.

DESIGN
Parallel, randomized trial stratified by recruitment site. Interviewers assessing outcomes were blinded to treatment assignment. (ClinicalTrials.gov: NCT00511680).

SETTING
A senior center and participants' homes from 2008 to 2010.

PATIENTS
African Americans aged 55 years or older with depressive symptoms.

INTERVENTION
A multicomponent, home-based intervention delivered by social workers or a wait-list control group that received the intervention at 4 months.

MEASUREMENTS
Self-reported depression severity at 4 months (primary outcome) and depression knowledge, quality of life, behavioral activation, anxiety, function, and remission at 4 and 8 months.

RESULTS
Of 208 participants (106 and 102 in the intervention and wait-list groups, respectively), 182 (89 and 93, respectively) completed 4 months and 160 (79 and 81, respectively) completed 8 months. At 4 months, participants in the intervention group showed reduced depression severity (difference in mean change in Patient Health Questionnaire-9 score from baseline, -2.9 [95% CI, -4.6 to -1.2]; difference in mean change in Center for Epidemiologic Studies Depression Scale score from baseline, -3.7 [CI, -5.4 to -2.1]); improved depression knowledge, quality of life, behavioral activation, and anxiety (P < 0.001); and improved function (P = 0.014) compared with wait-list participants. More intervention than wait-list participants entered remission at 4 months (43.8% vs. 26.9%). After treatment, control participants showed benefits similar in magnitude to those of participants in the initial intervention group. Those in the initial intervention group maintained benefits at 8 months.

LIMITATION
The study had a small sample, short duration, and differential withdrawal rate.

CONCLUSION
A home-based intervention delivered by social workers could reduce depressive symptoms and enhance quality of life in most older African Americans.

PRIMARY FUNDING SOURCE
National Institute of Mental Health.