A History of the Isolation and Identification of Vitamin B6

  title={A History of the Isolation and Identification of Vitamin B6},
  author={Irwin H. Rosenberg},
  journal={Annals of Nutrition and Metabolism},
  pages={236 - 238}
  • I. Rosenberg
  • Published 1 November 2012
  • Biology
  • Annals of Nutrition and Metabolism
In the 1930s, Rudolf Peters showed that young rats kept on a semi-synthetic diet with added thiamin and riboflavin but no other supplement developed ‘rat acrodynia’, a condition characterized by severe cutaneous lesions. In 1934, Paul György showed that the factor which cured ‘rat acrodynia’ was vitamin B6. Other studies soon showed that vitamin B6 deficiency produced convulsions in rats, pigs, and dogs, and a microcytic anemia in certain animals. Samuel Lepkovsky isolated and crystallized… 

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