• DOI:10.3390/molecules25081780
Corpus ID: 215793608

A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity

@article{TavarezSantamara2020AHF,
  title={A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity},
  author={Zaira Tavarez-Santamar{\'i}a and N. Jacobo-Herrera and L. Rocha-Zavaleta and A. Zentella-Dehesa and Beatriz del Carmen Couder-Garc{\'i}a and M. Mart{\'i}nez-V{\'a}zquez},
  journal={Molecules},
  year={2020},
  volume={25}
}

Zaira Tavarez-Santamaría, N. Jacobo-Herrera, +3 authors M. Martínez-Vázquez

Published 2020

Chemistry, Medicine

Molecules

Parthenium argentatum (Gray), commonly known as guayule, has been used to obtain natural rubber since the beginning of the 20th century. Additionally, the so called “resin” is a waste product derived from the industrial process. The cycloartane-type triterpene Argentatin A (AA) is one of the main constituents of the industrial waste resin. In this study we evaluated the AA anticancer activity both in vitro and in vivo in the HCT116 colon cancer cells. The apoptosis promotion of AA was assessed… CONTINUE READING

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