A High-Throughput Screen for Tuberculosis Progression

@article{Carvalho2011AHS,
  title={A High-Throughput Screen for Tuberculosis Progression},
  author={R. Carvalho and J. de Sonneville and Oliver W. Stockhammer and N. Savage and Wouter J. Veneman and T. Ottenhoff and R. Dirks and A. Meijer and H. Spaink},
  journal={PLoS ONE},
  year={2011},
  volume={6}
}
One-third of the world population is infected with Mycobacterium tuberculosis and multi-drug resistant strains are rapidly evolving. The noticeable absence of a whole organism high-throughput screening system for studying the progression of tuberculosis is fast becoming the bottleneck in tuberculosis research. We successfully developed such a system using the zebrafish Mycobacterium marinum infection model, which is a well-characterized model for tuberculosis progression with biomedical… Expand
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