A High Throughput Genetic Screen Identifies New Early Meiotic Recombination Functions in Arabidopsis thaliana

@inproceedings{Muyt2009AHT,
  title={A High Throughput Genetic Screen Identifies New Early Meiotic Recombination Functions in Arabidopsis thaliana},
  author={Arnaud de Muyt and Lucie Pereira and Daniel Vezon and Liudmila Chelysheva and Ghislaine Gendrot and Aur{\'e}lie Chambon and Sandrine Lain{\'e}-Choinard and G. Pelletier and Rapha{\"e}l Mercier and Fabien Nogu{\'e} and Mathilde Grelon},
  booktitle={PLoS genetics},
  year={2009}
}
Meiotic recombination is initiated by the formation of numerous DNA double-strand breaks (DSBs) catalysed by the widely conserved Spo11 protein. In Saccharomyces cerevisiae, Spo11 requires nine other proteins for meiotic DSB formation; however, unlike Spo11, few of these are conserved across kingdoms. In order to investigate this recombination step in higher eukaryotes, we took advantage of a high-throughput meiotic mutant screen carried out in the model plant Arabidopsis thaliana. A collection… CONTINUE READING

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