A Heterogeneous In Vitro Three Dimensional Model of Tumour-Stroma Interactions Regulating Sprouting Angiogenesis

@inproceedings{Sampaio2012AHI,
  title={A Heterogeneous In Vitro Three Dimensional Model of Tumour-Stroma Interactions Regulating Sprouting Angiogenesis},
  author={Pedro Correa de Sampaio and David Auslaender and Davia Krubasik and Antonio Virgilio Failla and Jeremy N. Skepper and Gillian Murphy and William R English},
  booktitle={PloS one},
  year={2012}
}
Angiogenesis, the formation of new blood vessels, is an essential process for tumour progression and is an area of significant therapeutic interest. Different in vitro systems and more complex in vivo systems have been described for the study of tumour angiogenesis. However, there are few human 3D in vitro systems described to date which mimic the cellular heterogeneity and complexity of angiogenesis within the tumour microenvironment. In this study we describe the Minitumour model--a 3… CONTINUE READING

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