• Corpus ID: 52200536

A HPLC Method for the Determination of Bisoprolol in Tablets and its Application to a Bioequivalence Study

@inproceedings{Panainte2015AHM,
  title={A HPLC Method for the Determination of Bisoprolol in Tablets and its Application to a Bioequivalence Study},
  author={Alina Diana Panainte and Luminița Agoroaei and Nela Bibire and Gladiola Ț{\^a}ntaru and Mihai Apostu and Mădălina Vieriu and Florin Adrian Spac},
  year={2015}
}
ALINA-DIANA PANAINTE1, LUMINITA AGOROAEI2*, NELA BIBIRE1, GLADIOLA TANTARU1, MIHAI APOSTU1, MADALINA VIERIU1, FLORIN ADRIAN SPAC3 1 “Grigore T. Popa“ University of Medicine and Pharmacy, Faculty of Pharmacy, Analytical Chemistry, 15 University Str., 700115, Iasi, România 2 “Grigore T. Popa“ University of Medicine and Pharmacy, Faculty of Pharmacy, Toxicology, 15 University Str., 700115, Iasi, România 3 “Grigore T. Popa“ University of Medicine and Pharmacy, Faculty of Pharmacy, Physical… 
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9 Citations
Background Citations
1
Methods Citations
4

Figures and Tables from this paper

9 Citations

HPLC METHOD DEVELOPMENT FOR THE ANALYSIS OF BISOPROLOL IN COMBINED DOSAGE FORM CONTAINING BISOPROLOL AND ENALAPRIL AND IN VITRO DISSOLUTION STUDIED
TLDR
A simple, rapid and reproducible HPLC method was developed and applied successfully for quality control assay of bisoprolol in experimental tablets and in vitro dissolution studies.
EVALUATION OF QUALITATIVE AND QUANTITATIVE STABILITY PARAMETERS OF A NEW TABLET FORMULATION CONTAINING BISOPROLOL FUMARATE
TLDR
Evaluation of modified release tablets of bisoprolol fumarate formulated using hydroxypropyl methylcellulose and Precirol ATO5 excipients showed that the obtained tablets were stable under stress condition for at least 6 months and did not show any significant changes regarding their appearance and drug content.
Novel Trends in Analytical Methods for β-Blockers: An Overview of Applications in the Last Decade
TLDR
An overview of the analytical methods for determination of β-blockers in pharmaceuticals, biological fluids, and environmental samples is provided to provide an overview of their reliability, high specificity, and fast response.
Reversed‐phase–high‐performance liquid chromatography method simultaneous quantification of Ivabradine HCl and Bisoprolol fumarate
Comparison of in vitro dissolution of Bisoprolol Fumarate tablets of five Brands marketed in Aden, Yemen
Bisoprolol fumarate is a selective β-1 blocker and is useful in the management of cardiovascular diseases. According to Biopharmaceutical Drug Classification System, it is a class I drug, which has…
Determination of Enalapril maleate from tablets using a new HPLC method
Abstract For the determination of enalapril maleate in tablets a new, simple and economical HPLC method was developed and fully validated. Chromatographic separation was achieved on Hewlett Zorbax…
Bisoprolol: A comprehensive profile.
ANALYSIS OF APPROACHES TO THE DEVELOPMENT AND VALIDATION OF THE METHODS OF ANALYSIS OF BISOPROLOL IN DRUGS AND BIOLOGICAL LIQUIDS
  • L. Logoyda
  • Chemistry
    Medical and Clinical Chemistry
  • 2019
TLDR
It is shown that HPLC is the most suitable method for analyses of bisoprolol in substances, drugs, biological liquids to perform routine analysis of medicines, pharmacokinetic (bioequivalence in vivo), dissolution test for final dosages forms.
Simultaneous Spectrophotometric Estimation of Bisoprolol Fumarate and Hydrochlorothiazide in Tablet Formulation using Partial Least-Squares, Principal Component Regression Multivariate Calibrations and RP-HPLC Methods
J Anal Pharm Res 2017, 4(6): 00124 Abstract The UV spectrophotometric analysis of a binary mixture containing bisoprolol fumarate (BS) and hydrochlorothiazide (HZ) by using multivariate calibration…

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