A Green Light-Triggerable RGD Peptide for Photocontrolled Targeted Drug Delivery: Synthesis and Photolysis Studies.

Abstract

We describe for the first time the synthesis and photochemical properties of a coumarin-caged cyclic RGD peptide and demonstrate that uncaging can be efficiently performed with biologically compatible green light. This was accomplished by using a new dicyanocoumarin derivative (DEAdcCE) for the protection of the carboxyl function at the side chain of the… (More)

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Cite this paper

@article{Gandioso2016AGL, title={A Green Light-Triggerable RGD Peptide for Photocontrolled Targeted Drug Delivery: Synthesis and Photolysis Studies.}, author={Albert Gandioso and Marc Cano and Anna Massaguer and Vicente March{\'a}n}, journal={The Journal of organic chemistry}, year={2016}, volume={81 23}, pages={11556-11564} }