A Great Barrier Reef Sinularia sp. Yields Two New Cytotoxic Diterpenes

  title={A Great Barrier Reef Sinularia sp. Yields Two New Cytotoxic Diterpenes},
  author={Anthony David Wright and Jonathan L. Nielson and Dianne M. Tapiolas and Catherine H. Liptrot and Cherie A. Motti},
  journal={Marine Drugs},
  pages={1619 - 1630}
The methanol extract of a Sinularia sp., collected from Bowden Reef, Queensland, Australia, yielded ten natural products. These included the new nitrogenous diterpene (4R*,5R*,9S*,10R*,11Z)-4-methoxy-9-((dimethylamino)-methyl)-12,15-epoxy-11(13)-en-decahydronaphthalen-16-ol (1), and the new lobane, (1R*,2R*,4S*,15E)-loba-8,10,13(14),15(16)-tetraen-17,18-diol-17-acetate (2). Also isolated were two known cembranes, sarcophytol-B and (1E,3E,7E)-11,12-epoxycembratrien-15-ol, and six known lobanes… 

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