A Glu487Lys polymorphism in the gene for mitochondrial aldehyde dehydrogenase 2 is associated with myocardial infarction in elderly Korean men.

@article{Jo2007AGP,
  title={A Glu487Lys polymorphism in the gene for mitochondrial aldehyde dehydrogenase 2 is associated with myocardial infarction in elderly Korean men.},
  author={Sangmee Ahn Jo and Eun-Kyung Kim and Moon Ho Park and Changsu Han and Harriet Park and Yangsoo Jang and Byung Joon Song and Inho Jo},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2007},
  volume={382 1-2},
  pages={43-7}
}
BACKGROUND A homozygous mutant (ALDH2*2/*2) of the gene for mitochondrial aldehyde dehydrogenase 2 (ALDH2) at codon 487 was reported to be associated with myocardial infarction (MI) among Japanese men. However, such an association has never been studied in a Korean population. METHOD The subjects consisted of 122 men (60-81 y) with MI recruited randomly from Yonsei University Medical Center, Korea. A total of 439 men (60-84 y) without MI were selected as controls from the Ansan Geriatric… CONTINUE READING

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