A Global Structural EM Algorithm for a Model of Cancer Progression

@inproceedings{Tofigh2011AGS,
  title={A Global Structural EM Algorithm for a Model of Cancer Progression},
  author={Ali Tofigh and Erik Sj{\"o}lund and Mattias H{\"o}glund and Jens Lagergren},
  booktitle={NIPS},
  year={2011}
}
Cancer has complex patterns of progression that include converging as well as diverging progressional pathways. Vogelstein's path model of colon cancer was a pioneering contribution to cancer research. Since then, several attempts have been made at obtaining mathematical models of cancer progression, devising learning algorithms, and applying these to cross-sectional data. Beerenwinkel et al. provided, what they coined, EM-like algorithms for Oncogenetic Trees (OTs) and mixtures of such. Given… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Computational Modeling of Cancer Progression

VIEW 5 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Computational Cancer Biology: An Evolutionary Perspective

  • PLoS Computational Biology
  • 2016
VIEW 2 EXCERPTS
CITES METHODS
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 21 REFERENCES