A Glial K/Cl Transporter Controls Neuronal Receptive Ending Shape by Chloride Inhibition of an rGC

@article{Singhvi2016AGK,
  title={A Glial K/Cl Transporter Controls Neuronal Receptive Ending Shape by Chloride Inhibition of an rGC},
  author={Aakanksha Singhvi and Bingqian Liu and Christine J. Friedman and Jennifer Y Fong and Yun Lu and X. X. Huang and Shai Shaham},
  journal={Cell},
  year={2016},
  volume={165},
  pages={936-948}
}
Neurons receive input from the outside world or from other neurons through neuronal receptive endings (NREs). Glia envelop NREs to create specialized microenvironments; however, glial functions at these sites are poorly understood. Here, we report a molecular mechanism by which glia control NRE shape and associated animal behavior. The C. elegans AMsh glial cell ensheathes the NREs of 12 neurons, including the thermosensory neuron AFD. KCC-3, a K/Cl transporter, localizes specifically to a… CONTINUE READING

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