A Glass of Water Immediately Increases Gastric pH in Healthy Subjects

@article{Karamanolis2008AGO,
  title={A Glass of Water Immediately Increases Gastric pH in Healthy Subjects},
  author={George P. Karamanolis and Ioanna Theofanidou and Marina Yiasemidou and Evangelos Giannoulis and Konstantinos Triantafyllou and Spiros D Ladas},
  journal={Digestive Diseases and Sciences},
  year={2008},
  volume={53},
  pages={3128-3132}
}
Onset of action of antisecretory agents is of pivotal importance for patients with gastroesophageal reflux disease (GERD) treated “on-demand.” Aim To study the acute effect of acid-inhibiting drugs and water administration on gastric pH. Method A cross-over study was performed in 12 H. pylori (-), healthy subjects (6 men; mean age: 26 years). A single oral dose of the following agents was received with a wash-out period between each study: a glass of water (200 ml), antacid, ranitidine… CONTINUE READING