A Genome-Wide Longitudinal Transcriptome Analysis of the Aging Model Podospora anserine

@inproceedings{Philipp2013AGL,
  title={A Genome-Wide Longitudinal Transcriptome Analysis of the Aging Model Podospora anserine},
  author={Oliver Philipp and Andrea Hamann and J{\"o}rg Servos and Alexandra B. Werner and Ina Koch and Heinz D. Osiewacz},
  booktitle={PloS one},
  year={2013}
}
Aging of biological systems is controlled by various processes which have a potential impact on gene expression. Here we report a genome-wide transcriptome analysis of the fungal aging model Podospora anserina. Total RNA of three individuals of defined age were pooled and analyzed by SuperSAGE (serial analysis of gene expression). A bioinformatics analysis identified different molecular pathways to be affected during aging. While the abundance of transcripts linked to ribosomes and to the… CONTINUE READING