A Genome-Wide, Fine-Scale Map of Natural Pigmentation Variation in Drosophila melanogaster

@inproceedings{Bastide2013AGF,
  title={A Genome-Wide, Fine-Scale Map of Natural Pigmentation Variation in Drosophila melanogaster},
  author={H{\'e}lo{\"i}se Bastide and Andrea Alejandra Betancourt and Viola Nolte and Raymond Tobler and Petra Stoebe and Andreas Futschik and Christian Schl{\"o}tterer},
  booktitle={PLoS genetics},
  year={2013}
}
Various approaches can be applied to uncover the genetic basis of natural phenotypic variation, each with their specific strengths and limitations. Here, we use a replicated genome-wide association approach (Pool-GWAS) to fine-scale map genomic regions contributing to natural variation in female abdominal pigmentation in Drosophila melanogaster, a trait that is highly variable in natural populations and highly heritable in the laboratory. We examined abdominal pigmentation phenotypes in… CONTINUE READING

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